William Moore, Ph.D.
Biography
Dr. William Moore specializes in diabetes, metabolism, and medical microbiology. His research focuses on identifying naturally occurring compounds with anti-diabetic potential and elucidating their mechanisms of action in adipocytes. He also screens naturally occurring compounds for their pro- and anti-bacterial potential in gut microbial species linked to metabolic health and investigates how these compounds influence glucose metabolism in renal cell carcinoma cells.
Dr. Moore discovered his passion for teaching while instructing his first microbiology course in 2010 and has since dedicated his career to both research and education. He received formal training in evidence-based teaching methods during his doctoral studies at Virginia Tech. Before joining Liberty University, Dr. Moore served as an assistant professor of biology at Averett University and taught a wide range of biomedical science courses at Fort Hays State University, Kansas State University, Virginia Tech, and within the Virginia Community College System.
Courses Taught
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BIOL203 – Introductory Microbiology
- BIOL203L – Introductory Microbiology Lab
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BCHM450 – Medical Biochemistry
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BIOL495 – Undergraduate Research
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BIOM600 – Biomedical Ethics
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BIOM750 – Research Rotation
Research Interests
- Diabetes and metabolism
- Natural product pharmacology
- Gut microbiota
- Cancer metabolism
Professional Membership
- American Diabetes Association
- American Society of Nutrition
- Virginia Academy of Science
Publications
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Madzinge V, Moore WT, Winter J. P300 enhances the phosphorylation of IRS-1 S1101 by P70S6K1. 2025. Current Developments in Nutrition.
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Smith M, Bayliss E, Dautaj E, Chung J, Ekoh F, Donkor O, Madzinge V, Becker MH, Moore WT. 24-Methyl Cholesterol Modulates NAMPT Activity and Glucose Metabolism in Renal Cell Carcinoma. 2025. Current Developments in Nutrition.
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Baylis E, Smith M, Miller R, Chung J, Bosch H, Mankos O, Woodfin S, Bones M, Becker MH, Madzinge V, Moore WT. Enterococcus faecalis Metabolizes Matairesinol to Enterolactone, which Promotes E. faecalis Growth and Glut4-Dependent Glucose Uptake in Adipocytes. 2025 Current Developments in Nutrition.
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Eastham G, Fausnacht D, Becker MH, Gillen, A, Moore WT. Praziquantel resistance in schistosomes: A brief report. 2024. Frontiers in Parasitology.
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Woodfin SF, Hall S, Ramerth A, Chapple B, Fausnacht D, Moore WT, Alkhalidy H, Liu D. Potential application of plant-derived compounds in multiple sclerosis management. 2024. Nutrients.
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Ramerth A, Chapple B, Winter J, Moore WT. The other side of the perfect cup: coffee-derived non-polyphenols and their roles in mitigating factors affecting the pathogenesis of type-2 diabetes. International Journal of Molecular Sciences.
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Miller R, Frommack A, Woodfin SF, Chapple B, Bones M, Jampole S, Moore WT. 2024. Matairesinol and its metabolite enterolactone promote glucose uptake in 3T3-L1 adipocytes via a Glut4/Akt-dependent mechanism. Journal of Diabetes Abstract Supplement. 2030-LB.
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Chapple BE, Woodfin SF, Moore WT. 2024. The perfect cup? Coffee-derived polyphenols and their roles in mitigating factors affected type-2 diabetes pathogenesis. Molecules.
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Moore WT, Luo, J, Liu D. 2023. Kaempferol improves glucose uptake in skeletal muscle via an AMPK-dependent mechanism. Food Science and Human Wellness.
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Moore W. 2022 Personalized advising that is purposely inconsistent: the constants of great advisors and the variability that demands adaptability. In: Wesfall-Rudd D, Vengrin C, and Elliott-Engel J (eds.) Teaching in the University: Learning from graduate students and early-career faculty. Blacksburg: Virginia Tech College of Agriculture and Life Sciences. https://doi.org/10.21061/universityteaching.
- Alkhalidy HA, Moore WT, Wang Y, Luo J, McMillan RP, Zhen W, Zhou K, Liu D. 2018. The flavonoid kaempferol ameliorates streptozotocin-induced diabetes by suppressing hepatic glucose production. Molecules.
- Bowser SM, Moore WT, McMillan RP, Dorenkott M, Goodrich K, Ye L, O’Keefe S, Hulver MW, Neilson A. 2016. High molecular weight cocoa procyanidins possess enhanced insulin-enhancing and insulin mimetic activities in primary human skeletal muscle cells compared to smaller procyanidins. Journal of Nutritional Biochemistry.
- Wang A, Luo J, Moore WT, Alkhalidy H, Wu L, Zhang J, Zhen W, Wang Y, Clegg DJ, Xu B, Cheng Z, McMillan RP, Hulver MW, Liu D. 2016. GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro. Scientific Reports.
- Moore WT, Bowser SM, Fausnacht DW, Staley LL, Suh KS, Liu D. 2015. Beta-cell function and the nutritional state: Dietary factors that influence insulin secretion. Current Diabetes Reports.
- Moore WT, Sekavec JG, Zwenger SR, and Gillock ET. 2014. Continuous exposure of Staphylococcus epidermidis SE1457 to triclosan results in marked triclosan resistance due to a mutation in fab1. Transactions of the Kansas Academy of Science. 117:55-60.
- Sekavec JG, Moore WT, Gillock ET. 2013. Chlorhexidine resistance in a Gram-negative bacterium isolated from an aquatic source. Journal of Environmental Science and Health Part A, Toxic/Hazardous Substances & Environmental Engineering. 48: 1829-34.
- Varahan S, Iyer V, Moore WT, Hancock LE. 2013. Eep confers lysozyme resistance to Enterococcus faecalis via the activation of the ECF sigma factor, SigV. Journal of Bacteriology. 195:3125-34