Advanced Physiology and Pathophysiology – NURS 506

CG • Section 8WK • 11/08/2019 to 04/16/2020 • Modified 02/09/2022

Course Description

System-focused content addresses the normal physiologic and pathologic mechanisms of disease that serve as the foundation for advanced clinical assessment, decision-making, and management. Physiologic changes are compared and contrasted over the life span and developmental physiology, normal etiology, pathogenesis, and clinical manifestations of commonly found/observed altered health states and responses to illness and treatment modalities are examined.

For information regarding prerequisites for this course, please refer to the Academic Course Catalog.


Advanced practice nursing focuses not only on management of current disease states, but upon the prevention of disease advancement. Understanding the pathophysiology of disease process is critical to effectively evaluating the patient, planning care, and facilitating quality patient care.

Course Assignment

Textbook readings and lecture presentations

Course Requirements Checklist

After reading the Course Syllabus and Student Expectations, the student will complete the related checklist found in the Course Overview.

Discussion Assignments (3)

Discussions are collaborative learning experiences. Therefore, the student is required to post a thread of at least 500 words and post two replies of at least 250 words each.

For each thread, the student must include at least two scholarly citations published within the last 5 years in current APA format. Each reply must cite at least one source.

Annotated Bibliography Assignment

The student will identify five scholarly sources published within the last 5 years related to a clinical area of expertise. These sources should be peer-reviewed and valid (i.e., present a strong level of evidence). The student will provide a brief review of each article’s strengths and weaknesses. The sources must be cited in current APA format.

Case Study Assignments (2)

The student will write two case studies. Each case may be based on an actual or fictional patient (if actual, remember to leave out any identifying information). The student will develop a background of the patient including age, race, diagnosis, signs and symptoms, family history, social history, and medications/allergies. The case must include an in-depth discussion of the pathophysiology of the selected disease to the cellular level. The student will also discuss a holistic plan of care including any genetic counseling/testing, patient education, and physical, psychosocial, spiritual, and cultural care the patient should receive. The case study must be 3 to 4 pages (excluding the title and reference pages) and include at least 4 scholarly sources published within the last 5 years. The case studies should use current APA format.

Cardiovascular–Pulmonary Presentation Assignment

The student will develop a Microsoft PowerPoint presentation on a cardiovascular–pulmonary disorder/disease discussed in the McCance text. The presentation must provide information about the incidence, prevalence, and pathophysiology of the disease/disorder to the cellular level. The presentation must educate professional nurses on assessment and care/treatment specific to this disorder. Patient education for management, cultural, and spiritual considerations for care must also be addressed. The presentation must specifically address how the disease/disorder affects one of the following age groups: infant/child, adult, or elderly. The presentation must be at least 15 slides (excluding the title and reference slides) and include 3 to 5 scholarly sources published within the last 5 years and cited in current APA format.

Quizzes (6)

Each quiz will cover the Learn material. Each quiz is open-book and open-notes, contains 15 multiple-choice questions, and has a time limit of 30 minutes.

Quiz: Comprehensive Review

The Final Comprehensive Review will cover the Learn materials from Module 1: Week 1 — Module 6: Week 6. The quiz will consist of 25 multiple-choice questions and 1 essay question, be open-book and open-notes, and have a time limit of 1 hour and 30 minutes.